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Dankner R, Murad H, Agay N, Olmer L, Freedman LS
While clinical evidence does not show GLP-1 medications directly cause these conditions, baseline mental health status influences how any medicationincluding weight loss drugsmay be tolerated
This mechanism reduces endotoxin translocation and inhibits activation of the hepatic TLR4/NF-B inflammatory signaling pathway induced by LPS from Enterobacteriaceae
Reading these together, the case for the pairing is mechanistic and evidentiary rather than direct
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