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Fluorescence imaging is still considered the most used imaging tool to visualize cellular interaction of PLGA and other polymeric nanoparticle and has been recently extended to monitor their biodistribution in vivo 5

The HPV E6 protein interacts with the cellular E3 ligase E6AP, and this complex binds to the p53 DNA-binding domain, which results in degradation of p53

This method is considered particularly effective for conditions like non-alcoholic fatty liver disease, where intravenous glutathione has been used to support detoxification systems and combat oxidative stress

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