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No high-quality clinical trial has demonstrated that B12 injections produce meaningful weight loss outcomes independent of dietary and exercise changes
Some patients find relief by switching from semaglutide injection to oral semaglutide or tirzepatide, as different formulations and compounds engage GLP-1 and GIP receptors slightly differently, potentially producing different side effect profiles
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Older adults are more likely to use them for medical reasons, and younger adults are more likely to take them for weight loss
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