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We observed, that patients who developed PHLF displayed 2.3-fold higher GLP-1 plasma concentrations preoperatively, compared to patients without PHLF ( p = 0.030)

In the context of brain injury, excessive release of glutamate activates NMDA and AMPA receptors, which leads to a significant increase in the cytoplasmic Ca2+ concentration

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These insights, when interpreted with a qualified healthcare provider, can support more personalized medication selection and monitoring strategies