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We also describe the development of incretin-based pharmacotherapy, starting with exendin- 4 and ending with the identification of multi-incretin hormone receptor agonists, which appear to be the next major step in the fight against T2DM and obesity
Johansen MJ, Newman RA, Andreeff M , Konopleva M, Madden T
Similar lean-mass proportion is not the same as builds muscle or preserves all muscle automatically. Across obesity treatment generally, lean body mass loss still occurs with weight reduction, including with GLP-1based therapies, and newer expert commentary continues to emphasize muscle preservation as a major clinical priority
The sensitivity of GLP-1 analogues to temperature and light means that the manufacturing process must be rigorous
