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131 Recognizing these adaptive circuits enables the design of multiplexed therapeutic interventions to forestall resistance

Vukojevic et al., 2020) or existing vessel obstruction (Sikiric et al., 2014

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In atherosclerosis, lipid accumulation induces transdifferentiation of VSMCs into alternative phenotypes such as macrophage-like, foam cell-like, and osteochondrogenic-like, which contribute to plaque progression [6,7]

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