glp-1 효과 자연에서 찾은 해법…GLP-1 유사 효과, 천연물로 구현 가능할까 < 약대·학회 < 약국·약학 < 기사본문 당뇨병 치료제] GLP1 receptor agonists(GLP-1

Although PTX has therapeutic potential in chronic inflammatory and vascular diseases, but its clinical use is limited by poor bioavailability, rapid clearance, and dose-dependent side effects

Some studies have shown that angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers are better first-line therapy for patients with MetS, especially when type-2 diabetes is present

[44] They are highly transient, typically peaking during the initial 8-to-12-week dose-escalation phase before waning over time

The core mechanisms mainly include: 1) chronic hyperglycemia, leading to metabolic disorders (Doumani et al., 2025)