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Enhancement of anandamide formation in the limbic forebrain and reduction of endocannabinoid contents in the striatum of 9-tetrahydrocannabinol-tolerant rats

Figure 8 3.5 Chronic fatigue syndrome (CFS) A growing body of clinical evidence shows that the gut microbiota plays a critical role in CFS, with consistently observed reductions in butyrate-producing bacteria and enrichment of Enterobacteriaceae , together with frequent depletion of anti-inflammatory taxa such as Faecalibacterium (Knig et al., 2021

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The expression of ZO-1, Occludin, SIRT1, STAT3, p-STAT3, RORt, IL-6, IL-1, TNF-, and -actin was examined using the method previously described (Yao et al., 2014)