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The best time to take your GLP-1 shot can also influence how well you tolerate each dose increase
obesity + T2D, highest dose: Retatrutide: 28.3% 20.8% Semaglutide 7.2 mg: 20.7% 14.1% Orforglipron: 12.4% 10.5% Placebo-adjusted, retatrutide 12 mg delivered about two-thirds of the effect in type 2 diabetes that it delivered in the non-diabetic TRIUMPH-1 cohort 16.8 points versus 26.1 points
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