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Abstract Tumor metabolic reprogramming is a highly complex process that enables tumor survival in the presence of limited nutrients, involving multiple signaling pathways, non-coding RNAs (ncRNAs), and transcription factors
There was a 2015 Phase I human trial registered to study safety and pharmacokinetics, but published results are conspicuously missing
This competition can lead to elevated plasma and tissue drug concentrations, increasing the risk of toxicity (Fig
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