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ICP-MS analysis was used to determine the gold amount in the initial DDA-GSH-AuNCs suspension ( m initial ) and PLGA nanoparticle pellet ( m p ) as well as in the supernatant

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Interestingly, defects in mitochondrial energy metabolism are also present in the brains of patients with AD, leading to neuronal apoptosis and A deposition, which increases ROS production by interfering with mitochondrial calcium homeostasis and ETC function