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It may be one of the first peptides shown to act as a selective gene expression modulator, without the off-target chaos of pharmacological epigenetic drugs
Spatial and temporal precision in delivery and regulation Jia et al (185) demonstrated that adeno-associated virus-mediated Trx1 overexpression restricted to the hippocampus in APP/PS1 mice improved cognitive function without disrupting systemic redox homeostasis
Liu, L., Chen, J., Wang, L., Chen, C
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