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Developer: Eli Lilly and Company | Administration in Trials: Once-weekly subcutaneous injection First successful Phase 3 trial (TRIUMPH-4, topline Dec 2025): Up to 28.7% average body weight loss at 68 weeks (highest dose) in adults with obesity/overweight and knee osteoarthritis

Enhanced Fat Loss : Growth hormone can help to break down fat cells for energy, potentially leading to a reduction in body fat

Key Characteristics of Retatrutide Scientific studies explain how Retatrutide interacts with hormonal pathways that control appetite and energy management according to its peptide structure