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P to GSL : Appropriate when the medicine can be sold with reasonable safety outside of a pharmacy environment, meaning the hazard to health, risk of misuse, or need for special precautions is small, and wider sale is a convenience
however, pharmacokinetic interactions and safety considerations must be rigorously assessed
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Therefore, modified, engineered, and designer EVs represent a new development trend in this field, and these EVs could be of great clinical value if optimized and integrated properly
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