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Simulations suggest that glutathione pools are most sensitive to exposure duration at pharmacologically and supra-pharmacologically relevant doxorubicin concentrations
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In contrast, after intravenous administration of 1,000 mg acetaminophen, the plasma C max is 21.6 g/ml, AUC 06 is 42.5 g/h/ml, and AUC 0 is 50.0 g/h/ml
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