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7 , 8 , 9 , 89 Increasing lens ascorbate concentrations by only twofold is associated with protection against cataract-like damage
Intriguingly, MRI evidence of BBB disruption has been noted in seemingly normal white matter even before the emergence of enhancing lesions, as well as in non-enhancing regions, implying that BBB impairment precedes both clinical symptoms and other MRI-evident changes in the disease course
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