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NLRP3 is an inflammasome sensor protein that can perceive various DAMPs (danger-associated molecular patterns) and PAMPs (pathogen-associated molecular patterns)
En los ensayos clnicos STEP y SUSTAIN, los pacientes tratados con semaglutida experimentaron reducciones de triglicridos que oscilaron entre el 5% y el 15% comparado con placebo, dependiendo de la poblacin y la dosis
PMID 1326760
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