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A meta-analysis of 8 RCTs found that NAC supplementation significantly reduced fasting glucose (WMD: -5.84 mg/dL) and HbA1c (WMD: -0.27%) in people with metabolic conditions (Sarkaki et al., Clin Nutr ESPEN, 2021) [57]

These effects are generally most noticeable in the first 35 days and often improve as your body adapts

CDC, 2024, Adult Obesity Facts American Diabetes Association, Diabetes Complications: Cardiovascular Disease Evernorth Health Services, Emerging Trends and Growth Drivers in Health Care, 2023