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But Al-Aly says there may be more to it

Side Effects and Monitoring Requirements Reported adverse effects from clinical and observational data include injection-site erythema, facial flushing, dizziness, and transient hypotension occurring within 15 to 30 minutes of injection [5]

It does carry a higher cost and a shorter long-term research history than semaglutide, which is why a genuine medical evaluation matters before choosing between them

For example, in the SUSTAIN 5 clinical trial, patients with HbA1c levels of 8.0% or lower had their basal insulin doses reduced by 20% when starting semaglutide therapy to minimize the risk of low blood sugar