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Our model suggests that the large male-female differences in GSH concentration and the velocity of its synthesis cause females to be less sensitive to APAP toxicity compared to males
Moreover, its mechanisms for managing digestive precancerous lesions are concretely summarized, including anti-oxidative stress effects, anti-inflammatory response and regulation of cell proliferation and apoptosis, especially its modifications on TLR4/TRIF/NF-B signaling pathway and p53-dependent cell cycle control and apoptosis
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46 Chaves-FilhoA.EyresC.BlbaumL.LandwehrA.TremblayM
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