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Importantly, AOD9604 achieved these effects without activating the growth-promoting pathways that full-length growth hormone uses, which is why it doesnt cause the unwanted side effects of growth hormone therapy such as insulin resistance or abnormal growth
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This tells us that most of the weight loss benefit comes from reaching the 8mg level, with diminishing marginal returns above that
The pancreas releases both together after a meal, but while insulin manages where the nutrients go, amylin tells the brain and gut that food has arrived
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