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Firstly, activated NF-B and NLRP3 inflammasome in DN promotes inflammation and increases fibronectin and collagen deposition in kidney, 41,42 leading to thickening glomerular basement membrane, glomerular sclerosis, podocyte damage, and ultimately kidney fibrosis

Clinical, diagnostic, and therapeutic aspects of growth hormone deficiency during the transition period: review of the literature

Discussion Our study establishes that non-gene-edited hCiPSC-NSCs, delivered via a dual-pathway strategy (intravenous systemic + intracerebroventricular boost), concurrently ameliorate ASD-like phenotypes in VPA-exposed rats by targeting the gut-brain axis

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