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Clinical trials involving approximately 900 participants across six studies demonstrated excellent safety and tolerability
If tolerance is good and no adverse effects occur, increase to 75mg daily, often split into two doses of approximately 37.5mg each
Raises NAD+ and SAM The same study showed that NAD+ and S-adenosyl-methionine (SAM) both went up after NNMT inhibition
Most users report initial effects like increased energy within the first one to two weeks
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