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doi: 10.1002/eji.200737741 126
Activation of its receptor by GLP-1 can promote the phosphorylation of CREB, subsequently fostering the expression of genes related to neuronal survival and regeneration.396,397,398,399 GLP-1RAs and nerve cells GLP-1 can modulate peripheral nerves through the ERK (extracellular signal-regulated kinase) signaling pathway, reducing the occurrence of neurological dysfunction.400 Researchers have discovered that GLP-1RAs exhibit a noticeable increase in the level of phosphorylated ERK1/2 within the sciatic nerve of diabetic rats
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Improved Energy and Vitality: Many individuals feel energized and mentally alert for a short duration after the injection, making it an attractive alternative for humans with fatigue or low strength
