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The regulatory read Randomized, double-blind, placebo-controlled Co-primary endpoints: PASI 75 + sPGA 0/1 at Week 16 (standard registration bar) Protocol aligned with both FDA and EMA de-risks a dual US/EU submission path Accrual continues toward ~705 total participants Read this as a milestone, not a signal

By understanding its mechanisms of action from its influence on the gut-brain axis to its effects on insulin and glucagon we gain a deeper appreciation for its potential in improving the lives of individuals managing type 2 diabetes and struggling with weight

Mar 2013;20(2):165-174

N Engl J Med 2020;383:1436-46.ArticlePubMed 48