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Statistical significance among the three groups (control, semaglutide, and tirzepatide) was determined using a one-way analysis of variance (ANOVA), followed by Tukeys post-hoc test for multiple comparisons
Many participants in structured programs report an average body weight loss of 15% after 68 weeks, with some achieving losses exceeding 20-25% within a year
The injection can be given at any time of the day, with or without meals, and should be administered on the same day each week
A 2024 review surveyed neurotransmitter-system interactions in this body of work (PMID 38675421), suggesting the compound's effects on central nervous system tissue may share mechanisms with its peripheral activity
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