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Further mechanistic and prospective studies are required to establish a definitive causal relationship
Mller TD, Finan B, Bloom SR, DAlessio D, Drucker DJ, Flatt PR, Fritsche A, Gribble F, Grill HJ, Habener JF, et al
SIRT1 function is also modulated through protein-protein interactions: DBC1 inhibits SIRT1 activity via complex formation, 30,49 whereas AROS and SENP1 interact with SIRT1 to enhance its activity, expanding the spectrum of functional regulation
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