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Reported areas of investigation include angiogenesis (the formation of new blood vessels in tissue models), the modulation of inflammatory signaling, and cellular response in wound- and recovery-model systems
In mesothelioma models, SFN disrupts PRMT5/MEP50 complex function, inhibiting its methyltransferase activity, reactivating tumor suppressor expression, and suppressing cancer cell proliferation, invasion, and stem-like properties (79, 80)
Not for human or veterinary, diagnostic, or therapeutic use
These mitochondrial effects block both cell proliferation and differentiation [7]
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