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In experimental studies exploring the epigenetic effects of disrupted light-dark cycles, various types of epigenetic alterations (e.g., DNA methylation, histone modifications, and miRNA expression) have been observed across different animal models
Some plant-derived natural compounds, such as ferulic acid and quercetin, can alleviate levetiracetam-induced depressive symptoms without compromising its antiepileptic efficacy by inhibiting neuroinflammation-mediated activation of IDO [119, 120]
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