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Optic-disk cupping is a consequence of myriad disorders, but in this case its reduction is evidently due to a reduced oxidative insult, which also produces a better control of cell homeostasis with consequent rescue of astrocytes and nerve fibers
10.1097/QAD.0000000000002300 26 ChenJ.SunL.DingG.-B.ChenL.JiangL.WangJ.et al
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(34697528, 35521821) Various options to avoid this issue: Intravenous fosphenytoin avoids the issue entirely
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