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Collectively, this study provides a solid foundation for future exploration into the impact of NNMTi-and diet-mediated changes to the gut microbiome in obese and lean populations, as well as future targets to investigate mechanistically with NNMTi treatment

In practice, even well-designed studies can encounter issues, not because data are absent, but because they are fragmented or disconnected from the broader study context

In CBA mice, long-term administration of Epitalon preserved brain and liver mitochondrial ultrastructure, even after irradiation, suggesting real structural protection at the organ level [45]

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