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Though the outcome variables differed between these studies with some combination of total, muscle, adipose, and/or bone parameters measured, a relatively consistent pattern was seen across ARKO males, such that functional AR was necessary to maintain normal body mass, adiposity, trabecular and cortical bone composition, and to a more modest degree, lean mass and/or hindlimb skeletal muscle mass in adulthood

For patients seeking weight-loss medications outside of brand-name versions like Ozempic or Wegovy, compounded options can provide a more affordable alternative

Long-term daily use can damage the nerves in your colon and create worse constipation over time