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SAVOR-TIMI 53 additionally showed an increase in heart-failure hospitalization with saxagliptin [28][31]
Of note, the doses of liraglutide and dulaglutide used in these trials are the highest doses approved in Japan
10.1093/humrep/dei001
One nuance with blood testing: highly specialized research-grade assays like LC-HRMS (liquid chromatography high-resolution mass spectrometry) can detect peptide-based compounds in blood at very low concentrations
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