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Thus, glucose plays a fundamental role for glucagon secretion, yet the mechanisms involved in this phenomenon are unclear, including glucose sensing by the alpha cell

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After 12 h of incubation, partial separation of R123 and DND-99 signals suggested that some SSPH-MPN escaped from endolysosomes, further supporting that clathrin-mediated endocytosis as the primary cellular entry mechanism for SSPH-MPN [34]

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