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Research proposes that while it may influence senescence-associated pathways, it appears to preserve FOXO4s antioxidative transcriptional activity
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Human umbilical vein endothelial cells (HUVECs) culture HUVECs purchased from BCRC (Hsinchu, Taiwan, ROC) were grown in M199 medium supplemented with 16% fetal bovine serum and 20% EGM-2 (Clonetics, USA)
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