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Although clinical trials have failed to show their efficacy, a recent reanalysis of these studies suggested that these drugs may benefit AD patients with potentially greater therapeutic efficacy in those homozygous for the APOE 4 allele (Storck and Pietrzik, 2017), though it is not known whether the modulation of LRP-1 plays any role
It is specifically FDA-approved for treating type 2 diabetes in adults, playing a crucial role in managing blood sugar levels in individuals diagnosed with this condition
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