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Those given the supplement lost 11.9 pounds (5.4 kg) over 16 weeks, compared to only 2 pounds (0.9 kg) in the placebo group
Tirzepatide side effects Tirzepatide side effects center almost entirely on the gastrointestinal system
On one hand, FDA-approved obesity medications already exist (Wegovy, Zepbound, Foundayo), which historically has made priority review less likely for later entrants
The outcomes: Approved on first submission: 34% (286 requests) Denied, then approved on appeal with additional documentation: 29% (244 requests) Denied, appeal denied, patient switched to compounded semaglutide: 31% (260 requests) Denied, patient abandoned treatment: 6% (50 requests) The pattern that emerges: patients who succeed in getting Wegovy covered through Express Scripts are patients whose providers submitted complete documentation on the first attempt
