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This in turn leads to excessive storage of underutilized glucose in the liver (glycogenesis), the potential for developing fatty liver (ie, nonalcoholic steatohepatitis), and conversion of excess carbohydrates to fatty acids and triglycerides, with subsequent storage in adipose tissue
CKD can affect the metabolism of some nutrients, and supplementation may not be advisable in those with advanced CKD
In general, however, they start with the lowest dose they believe will be effective and will only increase the dose if an individual isn't getting relief from their symptoms
There are other GLP-1s besides Ozempic approved for type 2 diabetes: Mounjaro (tirzepatide) and Trulicity (dulaglutide)
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