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Appleton, The effects of low-calorie sweeteners on energy intake and body weight: a systematic review and meta-analyses of sustained intervention studies
While these existing tags have enjoyed an extremely wide adoption, they carry specific drawbacks: the very short tags represent peptides that can adopt disordered structures and thus trigger misfolding of the protein under study, while the full-length protein tags add a burden to the cellular machinery when the sometimes too-large fusion protein needs to be produced
Higher doses require more money than lower ones
Sep 2020;37(9):2081-2092
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