tirzepatide vs mazdutide The dual-receptor peptide that drove 20% weight loss in trials. is a once-weekly peptide that hits two receptors at once: glucagon and GLP-1. GLP-1 is the appetite side that cuts how mazdutide vs tirzepatide vs retatrutide

Curious

There are several good options right now: semaglutide (Wegovy), a GLP-1 receptor agonist medication tirzepatide (Zepbound), a GLP-1/GIP medication liraglutide (Saxenda), a GLP-1 medication Several oral medications are also approved by the FDA for weight loss, including: semaglutide (oral Wegovy) orforglipron (Foundayo) phentermine (Suprenza) naltrexone-bupropion (Contrave) orlistat (Xenical/Alli) These are FDA-approved for adults who have a BMI of 30 or higher or a BMI of 27 along with a weight-related condition such as type 2 diabetes, hypertension, high cholesterol, obstructive sleep apnea, cardiovascular disease, or MASH (metabolic dysfunction-associated steatohepatitis, previously dubbed fatty liver)

GLP-1RAs have been proposed to have anti-inflammatory properties

Tirzepatide initiation was associated with a lower risk of primary open-angle glaucoma compared with selective glucagon-like peptide-1 receptor agonists: risk ratio: 0.50