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Given that sensory or gastrointestinal adverse effects, such as dysgeusia and persistent nausea, can impair nutritional intake and lead to early treatment discontinuation (particularly in vulnerable populations) future research must incorporate rigorous sensory testing, larger and more diverse cohorts, and adherence-related outcomes to clarify how incretin therapies influence taste perception and long-term eating behavior (153, 157, 161)
Delayed treatment with 4-methylpyrazole protects against acetaminophen hepatotoxicity in mice by inhibition of c-jun n-terminal kinase
Absence of clinical safety data No Phase 1 clinical safety trial for BPC-157 has been completed and published
doi: 10.1016/j.phymed.2025.156901 158 PeiFDuanJTanLGuCMiaoJLiuSet al
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