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By analogy with findings in other cell types, MAMs may potentiate the activity of Ca 2+ -dependent enzymes in the TCA cycle by regulating Ca 2+ transfer between the ER and mitochondria, thereby potentially enhancing mitochondrial OXPHOS efficiency and ATP production
facilitating over-stimulated or sustained inflammatory responses with interferon and cytokine release, influencing ROS production, iron storage, platelet coagulability, cytokine production stimulation, regulation of fission and fusion, mitochondrial biogenesis, and interference of apoptosis and mitophagy (312319)
Freezing is generally not recommended as the freeze-thaw cycle can damage the peptide
C.JessenC.HufnagelA.SchmitzW.Xavier daS.Ferreira dos SantosA.et al (2023)
