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Bioavailability: nearly 100%, bypasses GI absorption entirely Deficiency: first-line for pernicious anemia and malabsorption Dosing: weekly to monthly maintenance Prescription: yes, through Heally At home: yes, after provider guidance Daily tablets or lozenges

NAD+ precursors like nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) increase NAD+ by providing substrate for the salvage pathway, while 5-Amino-1MQ increases NAD+ by inhibiting NNMT, the enzyme that removes nicotinamide from circulation

Translation beyond that controlled model is unestablished