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It supports mitochondrial function within neurons, helps recycle acetyl-CoA (which boosts production of the neurotransmitter acetylcholine), supports membrane and phospholipid production, and acts as an energy source for neural cells
The therapy is infused into the portal vein (similar to cadaveric islet transplants) and requires glucocorticoid-free immunosuppression to prevent rejection
This allows the supplement to pass through the gut lining and be delivered directly to the cells
This non-secretor genotype is a well-established risk factor for T1D and is associated with a different gut microbial community compared to secretor individuals (127, 128)
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