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Any episode of syncope (loss of consciousness) requires immediate medical assessment, as this may indicate significant hypotension or other serious conditions requiring investigation

Reddy's on April 28, 2026, and a second from Apotex on May 1, 2026, with Apotex's wholesale price reported near $78 for a four-week supply against roughly $240 for brand

Potential mechanisms include improved efficiency of myocardial glucose utilization, decreased systemic and pulmonary vascular resistance, activation of ischemic preconditioning pathways, chronotropism, improvement of systolic and diastolic function, among others (Aravindhan et al

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