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(I)Core Mechanism of Action: As a long-acting amylin analog, it enhances satiety and suppresses hunger through central regulation while improving control over food cravings, particularly for sweet and fatty foods
Adequate B12 helps ensure proper nerve function, which can improve coordination, reduce tingling or numbness (neuropathy), and support overall neurological health
In addition, metformin increased GSH synthesis to reduce ROS production and improved mitochondrial membrane potential and mitochondrial morphology, thereby increasing the survival of NSCs
Role of TLR4 in the gut-brain axis in Parkinsons disease: a translational study from men to mice
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