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Insulin levels may also decline as your body requires less insulin to maintain healthy glucose control, a sign that the medication is working to restore metabolic function
During the initial period, leukocyte-derived MMP-9 and brain-derived MMP-2 are involved, and later, MMP-3 and MMP-9, angiogenesis, and vasogenic edema may occur, which can destroy NVUs and exacerbate the destruction of the BBB [120, 121]
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