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FXR ligands are a second class of molecules also capable of reducing the levels of both inflammation and fibrosis in patient trials
Therefore, more extensive research is necessary to reveal the pathogenesis of MASH and to provide more effective treatments for MASH
Researchers attribute the drugs efficacy to its agonistic effects on the glucagon, GIP and GLP-1 receptors, indicating potential roles these receptors play in achieving the therapeutic effects of retatrutide
In women, particularly those with conditions like polycystic ovary syndrome (PCOS), weight loss can help normalize the hormonal landscape
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