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The lower limit values of quantification (LLOQ) in plasma samples was 2 ng ml 1 , and the exposure levels below the 75% of LLOQ (1.5 ng ml 1 ) were determined as below the limit of quantification (BLOQ)
Collectively, these studies suggest that selective targeting of myostatin has therapeutic potential in preserving muscle as part of pharmacologic weight management
Gummesson A, Nyman E, Knutsson M, Karpefors M (2017) Effect of weight reduction on glycated haemoglobin in weight loss trials in patients with type 2 diabetes
Efinopegdutide has been granted fast track designation by the FDA for the treatment of MASH (NCT04944992, NCT05877547) and this is the indication that the clinical development programme of this molecule will focus
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