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They were later FDA-approved for weight loss in 2014
At our Florida clinics we never prescribe it in isolation
When dose escalation to 12.5mg or 15mg is appropriate If you have been at 10mg for 12 or more weeks, have optimized nutrition and activity, and have confirmed a genuine plateau (no weight change for 8 or more consecutive weeks despite adherence), then escalation to 12.5mg may be warranted
(March 2013)
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